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Latanoprost may gradually change the eye colour by increasing the amount of brown pigment in the iris.
There is no experience of Latanoprost in inflammatory, neovascular, angle closure or congenital glaucoma and only limited experience in open angle glaucoma of pseudophakic patients and in pigmentary glaucoma. Latanoprost has no or little effect on the pupil but there is no experience in accurate attacks of closed angle glaucoma. Therefore it is recommended that Latanoprost should be used with caution in these conditions until more experience is obtained.
Macular oedema, including cystoid macular oedema, has been reported during treatment with Latanoprost. These reports have mainly occurred in aphakic patients, in pseudophakic patients with torn posterior lens capsule, or in patients with known risk factors for macular edema. Latanoprost should be used with caution in these patients.
Latanoprost should be used with caution during pregnancy and nursing women.
